Who We Are

Passage Bio is driven by a focused mission: to offer life-transforming therapies for individuals with CNS disorders, replacing their suffering with boundless possibilities.

Our company is dedicated to advancing promising gene therapies that address unmet medical needs. Our approach involves developing cutting-edge therapeutics that are underpinned by rigorous scientific research and state-of-the-art CMC analytics. Our team's unwavering commitment to excellence is the driving force behind our mission to revolutionize the lives of patients. We relentlessly push the boundaries of scientific discovery and medical advancement, aspiring to create a brighter future for those who depend on us.

Woman holding child

What We Bring to People Affected by CNS Diseases

A bold vision to fulfill the promise of gene therapy by delivering life-transforming medicines that provide a cure for previously incurable diseases.

A differentiated approach to gene therapy development through our innovative research partnership with the world-renowned University of Pennsylvania’s Gene Therapy Program (GTP) and Orphan Disease Center.

A focused pipeline of optimized gene therapies for CNS disorders, including two clinical-stage programs focused on the following devastating diseases:

Our Critical Core Values

We are driven to deliver on our vision by core values that guide our everyday work.


  • Put patients at the center of every decision
  • Apply leading-edge science, based on a commitment to excellence
  • Make an impact that will transform the lives of patients
  • Act with integrity and make decisions based on what is right
  • Succeed together because we are all part of the solution

Our Commitment to the Community

Building lasting relationships with the communities we serve is a foundational element of our corporate mission. Our commitment includes the following activities:

  • Facilitate improved and earlier patient identification
  • Increase access to resources such as genetic testing and counseling
  • Amplify the voices of community members
  • Partner with advocacy groups on fundraising efforts and initiatives

Parents holding baby